Hollow hydroxyapatite microspheres as a device for controlled delivery of proteins
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چکیده
منابع مشابه
Mucoadhesive Microspheres as a Controlled Drug Delivery System for Gastroretention
Context: Drugs that are easily absorbed from the gastrointestinal tract (GIT) and have a short halflife are eliminated quickly from the blood circulation, require frequent dosing. To avoid this, the oral controlled release (CR) formulations have been developed in an attempt to release the drug slowly into the GIT and maintain a constant drug concentration in the serum for longer period of time....
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In the long-term management of ulcerative colitis patients, repeat dosing maybe required. Since 5-ASA is largely absorbed from the upper intestine, selective delivery of drugs into the colon may be regarded as a better method of drug delivery with fewer side effects and a higher efficacy. The aim of this study was to prepare and evaluate a double coated multiparticulate system for 5-ASA deliver...
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A new type of organophosphonic acid, (4,4'-(1,2-diphenylethene-1,2-diyl)bis(4,1-phenylene))bis(methylene)diphosphonic acid (PATPE), based on tetraphenylethene has been prepared, and its ester derivative exhibits the characteristic property of aggregation-induced emission (AIE) in DMSO-H2O solution. The PATPE is then fabricated into hydroxyapatite by a one-pot condensation process to form hollow...
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ژورنال
عنوان ژورنال: Journal of Materials Science: Materials in Medicine
سال: 2011
ISSN: 0957-4530,1573-4838
DOI: 10.1007/s10856-011-4250-6